OPRD1 antibody

Catalog No. ABIN303594

Product Details anti-OPRD1 Antibody

Target: OPRD1 (Opioid Receptor, delta 1 (OPRD1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This OPRD1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Purification: ProteinG affinity purified

Immunogen: hDOR expressing cell line

Isotype: IgG1

Application Details

Application Notes: WB 1.0 ug/mL. FCM 1.0 ug/mL. ICC 1.0 ug/mL. IP 1.0 ug/mL

Restrictions: For Research Use only

Handling

Concentration: 0.25 mg/ml

Buffer: PBS [containing 2 % Block Ace as a stabilizer, 0.1 %Proclin as a bacteriostat]

Preservative: ProClin

Target Details for OPRD1

Target: OPRD1 (Opioid Receptor, delta 1 (OPRD1))

Alternative Name: OPRD1 (opioid receptor, delta 1) (DOR) (OPRD1 Products)

Synonyms: OPRD antibody, DOR-1 antibody, Nbor antibody, mDOR antibody, opioid receptor delta 1 antibody, opioid receptor, delta 1 antibody, OPRD1 antibody, Oprd1 antibody

Background: OPRD1 (opioid receptor, delta 1), also known as DOR, belongs to the rhodopsin subfamily of G-protein-coupled receptor (GPCR) family. OPRD1 is consist of 372 amino acids and is located largely in the brain, active T cells. OPRD1 may be responsible for analgesia, dysphoria, immunopotentiation Activation of native T cells markedly up-regulates the expression of OPRD1 and OPRD1 modulates T cell proliferation, IL-2 production, chemotaxis, and intracellular signaling. Stimulating OPRD1 expressed by activated CD4+ T cells significantly suppresses the expression of HIV-1. In addition, it has been showed that activation of OPRD1 is neuroprotective against severe stress, such as hypoxia-, glutamate-induced cell injury.

Pathways: Protein targeting to Nucleus